BDBM689216 6-((5-chloro-3-(2,2,2- trifluoroethoxy)pyridin-2- yl)oxy)-1-methyl-N-(3-methyl- 1,1-dioxidothietan-3-yl)-1H- benzo[d]imidazole-2- carboxamide::US20240254114, Example 18

SMILES Cn1c(nc2ccc(Oc3ncc(Cl)cc3OCC(F)(F)F)cc12)C(=O)NC1(C)CS(=O)(=O)C1

InChI Key InChIKey=IBXBOMPGUYVKJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 689216   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 689216BDBM689216(US20240254114, Example 18 | 6-((5-chloro-3-(2,2,2-...)
Affinity DataIC50: 0.800nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 689216BDBM689216(US20240254114, Example 18 | 6-((5-chloro-3-(2,2,2-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using diolein/13C oleoyl-CoA as substrate by measuring [13C]18-triolein product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed