BDBM689225 5-[[3-(2,2-difluoroethoxy)-5- methyl-2-pyridyl]oxy]-3- methyl-N-(4-methyl-1,1- dioxo-thian-4-yl)imidazo[4,5- b]pyridine-2-carboxamide::US20240254114, Example 37

SMILES Cc1cnc(Oc2ccc3nc(C(=O)NC4(C)CCS(=O)(=O)CC4)n(C)c3n2)c(OCC(F)F)c1

InChI Key InChIKey=QZCPUUUDWQNXIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689225   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689225(US20240254114, Example 37 | 5-[[3-(2,2-difluoroeth...)
Affinity DataIC50: 29nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent