BDBM689226 5-[3-(2,2- difluoroethoxy)pyrazin-2- yl]oxy-3-methyl-N-(4-methyl- 1,1-dioxo-thian-4- yl)imidazo[4,5-b]pyridine-2- carboxamide::US20240254114, Example 38

SMILES Cn1c(nc2ccc(Oc3nccnc3OCC(F)F)nc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=GXDGMAMDZDBPTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689226   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689226(US20240254114, Example 38 | 5-[3-(2,2- difluoroeth...)
Affinity DataIC50: 20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent