BDBM689231 5-((5-fluoro-3-(2,2,2- trifluoroethoxy)pyridin- 2-yl)oxy)-3,6-dimethyl- N-(4-methyl-1,1-dioxido- tetrahydro-2H-thiopyran- 4-yl)-3H-imidazo[4,5- b]pyridine-2-carboxamide::US20240254114, Example 46

SMILES Cc1cc2nc(C(=O)NC3(C)CCS(=O)(=O)CC3)n(C)c2nc1Oc1ncc(F)cc1OCC(F)(F)F

InChI Key InChIKey=LPSVPMLOIOITCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689231   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689231(US20240254114, Example 46 | 5-((5-fluoro-3-(2,2,2-...)
Affinity DataIC50: 6.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent