BDBM689237 5-((5-chloro-3-(2,2-difluoroethoxy)pyridin- 2-yl)oxy)-1-((3-fluorooxetan-3-yl)methyl)- N-(4-methyl-1,1-dioxidotetrahydro-2H- thiopyran-4-yl)-1H-imidazo[4,5-b]pyridine- 2-carboxamide::US20240254114, Example 56

SMILES CC1(CCS(=O)(=O)CC1)NC(=O)c1nc2nc(Oc3ncc(Cl)cc3OCC(F)F)ccc2n1CC1(F)COC1

InChI Key InChIKey=HGPNABAYILHUQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689237   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689237(US20240254114, Example 56 | 5-((5-chloro-3-(2,2-di...)
Affinity DataIC50: 51nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent