BDBM689239 5-[[5-Fluoro-3-(2,2,2-trifluoroethoxy)- 2-pyridyl]methoxy]-3-methyl-N-(4- methyl-1,1-dioxo-thian-4- yl)imidazo[4,5-b]pyridine-2- carboxamide::US20240254114, Example 59

SMILES Cn1c(nc2ccc(OCc3ncc(F)cc3OCC(F)(F)F)nc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=AFVIRQQWXGEQQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689239   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689239(US20240254114, Example 59 | 5-[[5-Fluoro-3-(2,2,2-...)
Affinity DataIC50: 2.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent