BDBM689240 5-[2-(2,2-difluoropropoxy)butoxy]-3- methyl-N-(4-methyl-1,1-dioxo-thian-4- yl)imidazo[4,5-b]pyridine-2- carboxamide::US20240254114, Example 61

SMILES CCC(COc1ccc2nc(C(=O)NC3(C)CCS(=O)(=O)CC3)n(C)c2n1)OCC(C)(F)F

InChI Key InChIKey=QGIMEZQYAVJHKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689240   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689240(US20240254114, Example 61 | 5-[2-(2,2-difluoroprop...)
Affinity DataIC50: 44nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent