BDBM689249 6-[[5-chloro-3-(2,2- difluoropropoxy)-2- pyridyl]oxy]-1-methyl- N-(4-methyl-1,1-dioxo-thian-4- yl)imidazo[4,5-c]pyridine-2- carboxamide::US20240254114, Example 67

SMILES Cn1c(nc2cnc(Oc3ncc(Cl)cc3OCC(C)(F)F)cc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=RYFPMERZLMAUNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689249   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689249(US20240254114, Example 67 | 6-[[5-chloro-3-(2,2- d...)
Affinity DataIC50: 24nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent