BDBM689259 6-[[5-fluoro-3-(2,2,2-trifluoroethoxy)- 2-pyridyl]oxy]-1,7-dimethyl-N-(4- methyl-1,1-dioxo-thian-4- yl)imidazo[4,5-c]pyridine-2- carboxamide::US20240254114, Example 79

SMILES Cc1c(Oc2ncc(F)cc2OCC(F)(F)F)ncc2nc(C(=O)NC3(C)CCS(=O)(=O)CC3)n(C)c12

InChI Key InChIKey=MQVILEDRZSVZFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689259   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689259(US20240254114, Example 79 | 6-[[5-fluoro-3-(2,2,2-...)
Affinity DataIC50: 58nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent