BDBM689268 5-((5-chloro-3-(2,2- difluoroethoxy)pyridin-2- yl)oxy)-N-((1S,2R)-3,3- difluoro-2- hydroxycyclohex- yl)thiazolo[5,4-b]pyridine- 2-carboxamide::US20240254114, Example 96

SMILES O[C@@H]1[C@H](CCCC1(F)F)NC(=O)c1nc2ccc(Oc3ncc(Cl)cc3OCC(F)F)nc2s1

InChI Key InChIKey=FAWJWMZRKUOICQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689268   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689268(US20240254114, Example 96 | 5-((5-chloro-3-(2,2- d...)
Affinity DataIC50: 3.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent