BDBM689279 (S)-8-(6-amino-5-((2- (trifluoromethyl)pyridin-3- yl)thio)pyrazin-2-yl)-2-oxa-8- azaspiro[4.5]decan-4-amine::US12053470, Compound 10

SMILES N[C@@H]1COCC11CCN(CC1)c1cnc(Sc2cccnc2C(F)(F)F)c(N)n1

InChI Key InChIKey=HRZBBEFONKKGFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689279   

LigandPNGBDBM689279(US12053470, Compound 10 | (S)-8-(6-amino-5-((2- (t...)
Affinity DataIC50: 25nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent