BDBM689289 (3S,4S)-8-(6-amino-5-((2- amino-3-chloropyridin-4- yl)thio)pyrazin-2-yl)-3-ethyl-2- oxa-8-azaspiro[4.5]decan-4- amine::US12053470, Compound 17

SMILES CC[C@@H]1OCC2(CCN(CC2)c2cnc(Sc3ccnc(N)c3Cl)c(N)n2)[C@@H]1N

InChI Key InChIKey=BSPKRXNBXSLYTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689289   

LigandPNGBDBM689289(US12053470, Compound 17 | (3S,4S)-8-(6-amino-5-((2...)
Affinity DataIC50: 9nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent