BDBM689290 (2R,4R)-4-amino-8-(5-((2- amino-3-chloropyridin-4- yl)thio)pyrazin-2-yl)-8- azaspiro[4.5]decan-2-ol::US12053470, Compound 18

SMILES N[C@@H]1C[C@H](O)CC11CCN(CC1)c1cnc(Sc2ccnc(N)c2Cl)cn1

InChI Key InChIKey=VPCWGBLXOCIIMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689290   

LigandPNGBDBM689290(US12053470, Compound 18 | (2R,4R)-4-amino-8-(5-((2...)
Affinity DataIC50: 4.5nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent