BDBM689291 (1R,3R)-8-(5-((2-amino-3- chloropyridin-4-yl)thio)pyrazin- 2-yl)-3-methyl-8- azaspiro[4.5]decan-1-amine::US12053470, Compound 19

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1cnc(Sc2ccnc(N)c2Cl)cn1

InChI Key InChIKey=XDODTCSHMOQQKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689291   

LigandPNGBDBM689291(US12053470, Compound 19 | (1R,3R)-8-(5-((2-amino-3...)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent