BDBM689309 (R)-6-(1-amino-8- azaspiro[4.5]decan-8-yl)-3- (2,3-dichlorophenyl)-5-methyl- 2,5-dihydro-4H-pyrazolo[3,4- d]pyrimidin-4-one::US12053470, Compound 37

SMILES Cn1c(nc2n[nH]c(-c3cccc(Cl)c3Cl)c2c1=O)N1CCC2(CCC[C@H]2N)CC1

InChI Key InChIKey=AWCUGJTVKPBYHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689309   

LigandPNGBDBM689309(US12053470, Compound 37 | (R)-6-(1-amino-8- azaspi...)
Affinity DataIC50: 26nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent