BDBM689312 3-(6-amino-2-methylpyridin-3- yl)-6-((1R,3R)-1-amino-3- methyl-8-azaspiro[4.5]decan- 8-yl)-5-methyl-2,5-dihydro-4H- pyrazolo[3,4-d]pyrimidin-4-one::US12053470, Compound 40

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc2n[nH]c(-c3ccc(N)nc3C)c2c(=O)n1C

InChI Key InChIKey=PXWVEUAMAFDBCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689312   

LigandPNGBDBM689312(US12053470, Compound 40 | 3-(6-amino-2-methylpyrid...)
Affinity DataIC50: 16nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent