BDBM689313 (R)-3-(6-amino-2- methylpyridin-3-yl)-6-(1-amino- 3,3-difluoro-8- azaspiro[4.5]decan-8-yl)-5- methyl-2,5-dihydro-4H- pyrazolo[3,4-d]pyrimidin-4-one::US12053470, Compound 41

SMILES Cc1nc(N)ccc1-c1[nH]nc2nc(N3CCC4(CC(F)(F)C[C@H]4N)CC3)n(C)c(=O)c12

InChI Key InChIKey=JLWLVSCZOWTUQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689313   

LigandPNGBDBM689313(US12053470, Compound 41 | (R)-3-(6-amino-2- methyl...)
Affinity DataIC50: 9nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
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Date in BDB:
11/21/2024
Entry Details
US Patent