BDBM689314 6-((3S,4S)-4-amino-3-methyl- 2-oxa-8-azaspiro[4.5]decan-8- yl)-3-(3-chloro-2- (cyclopropylamino)pyridin-4- yl)-5-methyl-2,5-dihydro-4H- pyrazolo[3,4-d]pyrimidin-4-one::US12053470, Compound 42

SMILES C[C@@H]1OCC2(CCN(CC2)c2nc3n[nH]c(-c4ccnc(NC5CC5)c4Cl)c3c(=O)n2C)[C@@H]1N

InChI Key InChIKey=URUPFUYPXLMTMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689314   

LigandPNGBDBM689314(US12053470, Compound 42 | 6-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 36nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent