BDBM689315 2-((3S,4S)-4-amino-3-methyl- 2-oxa-8-azaspiro[4.5]decan-8- yl)-5-(3-chloro-2- methoxypyridin-4-yl)-3-methyl- 3,7-dihydro-4H-pyrrolo[2,3- d]pyrimidin-4-one::US12053470, Compound 43

SMILES COc1nccc(-c2c[nH]c3nc(N4CCC5(CO[C@@H](C)[C@H]5N)CC4)n(C)c(=O)c23)c1Cl

InChI Key InChIKey=BXVJYYGWZPCIII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689315   

LigandPNGBDBM689315(US12053470, Compound 43 | 2-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 26nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
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Date in BDB:
11/21/2024
Entry Details
US Patent