BDBM690395 3-chloro-N-[2,6-difluoro- 4-[2-(5-fluoro-3- pyridyl)ethynyl]phenyl] benzenesulfonamide::US12065399, Example 14

SMILES Fc1cncc(c1)C#Cc1cc(F)c(NS(=O)(=O)c2cccc(Cl)c2)c(F)c1

InChI Key InChIKey=BFXKICSXARYMOA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690395   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM690395(US12065399, Example 14 | 3-chloro-N-[2,6-difluoro-...)
Affinity DataEC50:  1.05E+3nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated. Cells were cultured according to s...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent