BDBM690419 N-[2,6-difluoro-4-[2-(5- fluoro-3- pyridyl)ethynyl]phenyl]-3- fluoro-2,5-dimethyl- benzenesulfonamide; 2,2,2-trifluoroacetic acid salt::US12065399, Example 38::US12065399, Example 56

SMILES Cc1cc(F)c(C)c(c1)S(=O)(=O)Nc1c(F)cc(cc1F)C#Cc1cncc(F)c1

InChI Key InChIKey=IDBLTQLDICCLIT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 690419   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM690419(US12065399, Example 38 | US12065399, Example 56 | ...)
Affinity DataEC50:  434nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated. Cells were cultured according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM690419(US12065399, Example 38 | US12065399, Example 56 | ...)
Affinity DataEC50:  1.47E+3nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated. Cells were cultured according to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent