BDBM690425 N-[2,6-difluoro-4-[2-(3- fluorophenyl)ethynyl] phenyl]-3-fluoro-2,5-dimethyl- benzenesulfonamide::US12065399, Example 45

SMILES Cc1cc(F)c(C)c(c1)S(=O)(=O)Nc1c(F)cc(cc1F)C#Cc1cccc(F)c1

InChI Key InChIKey=QSCYKLIHQNXFFW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690425   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM690425(US12065399, Example 45 | N-[2,6-difluoro-4-[2-(3- ...)
Affinity DataEC50:  1.32E+3nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated. Cells were cultured according to s...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent