BDBM690427 N-[2,6-difluoro-4-[2-(3- methoxyphenyl)ethynyl] phenyl]-3-fluoro-2,5- dimethyl- benzenesulfonamide::US12065399, Example 47

SMILES COc1cccc(c1)C#Cc1cc(F)c(NS(=O)(=O)c2cc(C)cc(F)c2C)c(F)c1

InChI Key InChIKey=BEHVBHJMKUIJIB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690427   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM690427(US12065399, Example 47 | N-[2,6-difluoro-4-[2-(3- ...)
Affinity DataEC50:  1.05E+3nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated. Cells were cultured according to s...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent