BDBM690435 3-chloro-N-(4-((5-chloropyridin-3-yl)ethynyl)-2,6-difluorophenyl)-2-methylbenzenesulfonamide::US12065399, Example 55

SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1c(F)cc(cc1F)C#Cc1cncc(Cl)c1

InChI Key InChIKey=AWXCJERNDZHKGX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690435   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM690435(US12065399, Example 55 | 3-chloro-N-(4-((5-chlorop...)
Affinity DataEC50:  1.92E+3nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated. Cells were cultured according to s...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent