BDBM690726 (R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3-dihydro-1H- inden-1-yl)-4-methylisoxazole-5- carboxamide::US12065436, Compound 115

SMILES Cc1cnoc1C(=O)N[C@@H]1CCc2cc(ccc12)-c1noc(n1)C1CC1

InChI Key InChIKey=SSKBAYSXXOJHDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690726   

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690726((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent