BDBM692370 US20240270732, Compound I-25

SMILES C[C@H]1Oc2ccc(cc2N(C)C(=O)[C@H]1NC(=O)c1ncn(Cc2ccccc2)n1)C#CCN1CCN(CC#Cc2ccc3O[C@H](C)[C@H](NC(=O)c4nnn(Cc5ccccc5)n4)C(=O)N(C)c3c2)CC1

InChI Key InChIKey=ZQBJDDSSYAVHTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 692370   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Chengdu Biobel Biotechnology Co.

US Patent
LigandPNGBDBM692370(US20240270732, Compound I-25)
Affinity DataIC50: 3.39nMAssay Description:The compound of the present invention and the control compound were dissolved in the assay buffer (50 mM Hepes pH 7.5, 50 mM NaCl, 30 mM MgCl2, 1 mM ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent