BDBM692375 US20240270732, Compound I-30::US20240270732, Compound I-31::US20240270732, Compound I-36

SMILES C[C@H]1Oc2ccc(cc2N(C)C(=O)[C@H]1NC(=O)c1ncn(Cc2ccccc2)n1)C#CCN1CCN(CC#Cc2ccc3OC[C@H](NC(=O)c4ncn(Cc5ccccc5)n4)C(=O)N(C)c3c2)CC1

InChI Key InChIKey=DTHKWIPESHHFJA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 692375   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Chengdu Biobel Biotechnology Co.

US Patent
LigandPNGBDBM692375(US20240270732, Compound I-31 | US20240270732, Comp...)
Affinity DataIC50: 2.62nMAssay Description:The compound of the present invention and the control compound were dissolved in the assay buffer (50 mM Hepes pH 7.5, 50 mM NaCl, 30 mM MgCl2, 1 mM ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Chengdu Biobel Biotechnology Co.

US Patent
LigandPNGBDBM692375(US20240270732, Compound I-31 | US20240270732, Comp...)
Affinity DataIC50: 2.95nMAssay Description:The compound of the present invention and the control compound were dissolved in the assay buffer (50 mM Hepes pH 7.5, 50 mM NaCl, 30 mM MgCl2, 1 mM ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Chengdu Biobel Biotechnology Co.

US Patent
LigandPNGBDBM692375(US20240270732, Compound I-31 | US20240270732, Comp...)
Affinity DataIC50: 4.36nMAssay Description:The compound of the present invention and the control compound were dissolved in the assay buffer (50 mM Hepes pH 7.5, 50 mM NaCl, 30 mM MgCl2, 1 mM ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent