BDBM692581 (7S)-11-chloro-12-cyclopropyl-9-(2,6-difluorophenyl)-3,7-dimethyl-2,4,5,8,13-pentazatricyclo[8.4.0.02,6]tetradeca-1::US20240270744, Example 2

SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ncc2-n2c(C)nnc12)C1CC1

InChI Key InChIKey=NZKKIJZWLOYHBC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 692581   

LigandPNGBDBM692581(US20240270744, Example 2 | (7S)-11-chloro-12-cyclo...)
Affinity DataKi:  12.6nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692581(US20240270744, Example 2 | (7S)-11-chloro-12-cyclo...)
Affinity DataKi:  143nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692581(US20240270744, Example 2 | (7S)-11-chloro-12-cyclo...)
Affinity DataKi:  3.29E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent