BDBM692587 US20240270744, Example 8::[(7S)-11-chloro-9-(2,6-difluorophenyl)-7-methyl-12-(trifluoromethyl)-2,3,5,8,13-pentazatricyclo[8.4.0.02,6]tetradeca-1

SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ncc2-n2nc(nc12)C(=O)N1CC(O)C1)C(F)(F)F

InChI Key InChIKey=VBEASATUUNKOCC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 692587   

LigandPNGBDBM692587(US20240270744, Example 8 | [(7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  2.5nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692587(US20240270744, Example 8 | [(7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  14.6nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692587(US20240270744, Example 8 | [(7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  48.8nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692587(US20240270744, Example 8 | [(7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  3.72E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent