BDBM692599 (10S)-6-chloro-8-(2,6-difluorophenyl)-10-methyl-5-(trifluoromethyl)-1,4,9,12-tetrazatetracyclo[9.6.0.02,7.013,17]heptadeca-2(7),3,5,8,11,13::US20240270744, Example 20

SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ncc2-n2c1nc1CCCc21)C(F)(F)F

InChI Key InChIKey=OMBYDOBDGZMYLJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 692599   

LigandPNGBDBM692599(US20240270744, Example 20 | (10S)-6-chloro-8-(2,6-...)
Affinity DataKi:  4.90nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692599(US20240270744, Example 20 | (10S)-6-chloro-8-(2,6-...)
Affinity DataKi:  11.8nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692599(US20240270744, Example 20 | (10S)-6-chloro-8-(2,6-...)
Affinity DataKi:  1.09E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent