BDBM692600 (7S)-11-chloro-9-(2,6-difluorophenyl)-N-(2-hydroxy-2-methyl-propyl)-7-methyl-12-(trifluoromethyl)-2,3,5,8,13-pentazatricyclo[8.4.0.02,6]tetradeca-1::US20240270744, Example 21

SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ncc2-n2nc(nc12)C(=O)NCC(C)(C)O)C(F)(F)F

InChI Key InChIKey=VOGVJHPIWHIJPW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 692600   

LigandPNGBDBM692600(US20240270744, Example 21 | (7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  10.7nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692600(US20240270744, Example 21 | (7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  72.3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

LigandPNGBDBM692600(US20240270744, Example 21 | (7S)-11-chloro-9-(2,6-...)
Affinity DataKi:  1.13E+4nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent