BDBM692634 7-((2S,5R)-2,5-diethyl-4-(4- (trifluoromethoxy)benzyl)piperazin- 1-yl)-4-methyl-2-(prop-1-en-2-yl)- 2,4-dihydro-5H-pyrazolo[4,3- b]pyridin-5-one::US20240270751, Compound A27

SMILES CC[C@@H]1CN([C@@H](CC)CN1Cc1ccc(OC(F)(F)F)cc1)c1cc(=O)n(C)c2cn(nc12)C(C)=C

InChI Key InChIKey=NLYQVYXXMVXTSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 692634   

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandPNGBDBM692634(7-((2S,5R)-2,5-diethyl-4-(4- (trifluoromethoxy)ben...)
Affinity DataIC50: 4.30nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandPNGBDBM692634(7-((2S,5R)-2,5-diethyl-4-(4- (trifluoromethoxy)ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent