BDBM692660 US20240270751, Compound A46b

SMILES C[C@H](N1C[C@H](C)N(C[C@H]1C)c1cc(=O)n(C)c2cn(CC#N)nc12)c1ccc2OCC(C)(C)Oc2c1

InChI Key InChIKey=AJDFSJHYKIXUCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 692660   

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandPNGBDBM692660(US20240270751, Compound A46b)
Affinity DataIC50: 21nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandPNGBDBM692660(US20240270751, Compound A46b)
Affinity DataIC50: 2.57E+3nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent