BDBM692802 2-(cyanomethyl)-7-((2S,5R)-5-ethyl-2-methyl-4-(1-(quinoxalin-6-yl)ethyl)piperazin-1-yl)-4-methyl-5-oxo-4,5-dihydro-2H-pyrazolo[4,3-b]pyridine-6-carbonitrile::US20240270751, Compound A156

SMILES CC[C@@H]1CN([C@@H](C)CN1C(C)c1ccc2nccnc2c1)c1c(C#N)c(=O)n(C)c2cn(CC#N)nc12

InChI Key InChIKey=UFIFLPBWWMWMKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 692802   

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandPNGBDBM692802(2-(cyanomethyl)-7-((2S,5R)-5-ethyl-2-methyl-4-(1-(...)
Affinity DataIC50: 18nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandPNGBDBM692802(2-(cyanomethyl)-7-((2S,5R)-5-ethyl-2-methyl-4-(1-(...)
Affinity DataIC50: 1.75E+3nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent