BDBM69342 MLS001007082::N-[3-[(2-phenyl-4-quinazolinyl)amino]phenyl]acetamide::N-[3-[(2-phenylquinazolin-4-yl)amino]phenyl]acetamide::N-[3-[(2-phenylquinazolin-4-yl)amino]phenyl]ethanamide::SMR000384461::cid_2549745

SMILES CC(=O)Nc1cccc(Nc2nc(nc3ccccc23)-c2ccccc2)c1

InChI Key InChIKey=IBCJHQBSQYNQJM-UHFFFAOYSA-N

Data  4 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 69342   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM69342(SMR000384461 | MLS001007082 | N-[3-[(2-phenylquina...)Copy SMILESCopy InChI

Affinity DataIC50: 224nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Pheophorbide A addition by Pheophorbide A as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM69342(SMR000384461 | MLS001007082 | N-[3-[(2-phenylquina...)Copy SMILESCopy InChI

Affinity DataIC50: 224nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Pheophorbide A addition by Pheophorbide A as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM69342(SMR000384461 | MLS001007082 | N-[3-[(2-phenylquina...)Copy SMILESCopy InChI

Affinity DataIC50: 278nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accu...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM69342(SMR000384461 | MLS001007082 | N-[3-[(2-phenylquina...)Copy SMILESCopy InChI

Affinity DataIC50: 278nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accu...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay

LigandBDBM69342(SMR000384461 | MLS001007082 | N-[3-[(2-phenylquina...)Copy SMILESCopy InChI

Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
7/29/2011
Entry Details
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