BDBM693809 1-(1-((1S,2S)-2-((2-(2,6- dioxopiperidin-3-yl)-1-oxoisoindolin- 5-yl)oxy)cyclohexyl)azetidin-3- yl)cyclobutane-1-carbonitrile::US20240287037, Example 23

SMILES O=C1N(Cc2cc(O[C@H]3CCCC[C@@H]3N3CC(C3)C3(CCC3)C#N)ccc12)C1CCC(=O)NC1=O

InChI Key InChIKey=FFGHFCHCWGXTDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693809   

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693809(1-(1-((1S,2S)-2-((2-(2,6- dioxopiperidin-3-yl)-1-o...)
Affinity DataEC50:  28nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent