BDBM693919 US20240287079, Example 87

SMILES Cc1ccc(-n2cc3c(=O)[nH]c(N4CCCC4)nc3n2)c(Cl)c1

InChI Key InChIKey=DLFCJXAKLBRAPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693919   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 693919BDBM693919(US20240287079, Example 87)
Affinity DataIC50: 5.10nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent