BDBM694039 US20240287079, Example 210

SMILES O=c1[nH]c(N2CCOCC2)nc2nn(-c3ccc(C4CC4)cc3C3CC3)cc12

InChI Key InChIKey=GLMJVKQAJJGHFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694039   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 694039BDBM694039(US20240287079, Example 210)
Affinity DataIC50: 7.30nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent