BDBM694042 US20240287079, Example 213

SMILES Cc1cc(Br)cc(C)c1-n1cc2c(=O)[nH]c(N3CCOC[C@H]3C)nc2n1

InChI Key InChIKey=JNDRLHGLUQJXRG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694042   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 694042BDBM694042(US20240287079, Example 213)
Affinity DataIC50: 6.80nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent