BDBM694075 US20240287079, Example 249

SMILES Cc1cc(C(F)(F)F)cc(C)c1-n1cc2c(=O)[nH]c(N3C[C@H]4C[C@@H]3CO4)nc2n1

InChI Key InChIKey=OBIIFBWUYWGNBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694075   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 694075BDBM694075(US20240287079, Example 249)
Affinity DataIC50: 3.30nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent