BDBM694140 US20240287079, Example 317

SMILES CO[C@@H]1CCN(c2nc3nn(-c4c(C)cc(C5CC5)cc4C)cc3c(=O)[nH]2)C1

InChI Key InChIKey=QNVBDAQPKRFCRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694140   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 694140BDBM694140(US20240287079, Example 317)
Affinity DataIC50: 5.20nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent