BDBM694194 (5S)-8-chloro-7-(2,6-difluorophenyl)-5-methyl-9-(trifluoromethyl)-5H-pyrimido[1,2-a][1,4]benzodiazepin-3-one::US20240287082, Example 10

SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ccc2-n2ccc(=O)nc12)C(F)(F)F

InChI Key InChIKey=AZUUZTGSFIEJEO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 694194   

LigandPNGBDBM694194((5S)-8-chloro-7-(2,6-difluorophenyl)-5-methyl-9-(t...)
Affinity DataKi:  3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694194((5S)-8-chloro-7-(2,6-difluorophenyl)-5-methyl-9-(t...)
Affinity DataKi:  54.6nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694194((5S)-8-chloro-7-(2,6-difluorophenyl)-5-methyl-9-(t...)
Affinity DataKi:  159nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694194((5S)-8-chloro-7-(2,6-difluorophenyl)-5-methyl-9-(t...)
Affinity DataKi:  6.12E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent