BDBM694200 (5S)-2,9-dibromo-8-chloro-7-(2,6-difluorophenyl)-5-methyl-5H-pyrimido[1,2-a][1,4]benzodiazepin-3-one::US20240287082, Example 16

SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2cc(Br)c(=O)nc12

InChI Key InChIKey=BRJUPRDHWLSIQW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 694200   

LigandPNGBDBM694200((5S)-2,9-dibromo-8-chloro-7-(2,6-difluorophenyl)-5...)
Affinity DataKi:  1.60nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694200((5S)-2,9-dibromo-8-chloro-7-(2,6-difluorophenyl)-5...)
Affinity DataKi:  8.30nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694200((5S)-2,9-dibromo-8-chloro-7-(2,6-difluorophenyl)-5...)
Affinity DataKi:  1.57E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent