BDBM694202 (5S)-8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-ethoxyvinyl]-5-methyl-9-(trifluoromethyl)-5H-pyrimido[1,2-a][1,4]benzodiazepin-3-one::US20240287082, Example 18

SMILES CCO\C=C\c1cn2-c3ccc(c(Cl)c3C(=N[C@@H](C)c2nc1=O)c1c(F)cccc1F)C(F)(F)F

InChI Key InChIKey=ZCWNRXBYGGRGBP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 694202   

LigandPNGBDBM694202((5S)-8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-etho...)
Affinity DataKi:  9.70nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694202((5S)-8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-etho...)
Affinity DataKi:  60.6nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694202((5S)-8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-etho...)
Affinity DataKi:  6.34E+3nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent