BDBM694209 8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-ethoxyvinyl]-9-(trifluoromethyl)-5H-pyrimido[1,2-a][1,4]benzodiazepin-3-one::US20240287082, Example 25

SMILES CCO\C=C\c1cn-2c(CN=C(c3c(F)cccc3F)c3c(Cl)c(ccc-23)C(F)(F)F)nc1=O

InChI Key InChIKey=ISHWTRZXWXXTKT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 694209   

LigandPNGBDBM694209(8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-ethoxyvin...)
Affinity DataKi:  9.40nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694209(8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-ethoxyvin...)
Affinity DataKi:  47.9nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

LigandPNGBDBM694209(8-chloro-7-(2,6-difluorophenyl)-2-[(E)-2-ethoxyvin...)
Affinity DataKi:  1.47E+4nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent