BDBM694248 5-(3-cyano-5-fluorophenoxy)-1,1,2,2-tetrafluoro-3- hydroxy-3-methyl-2,3-dihydro-1H-indene-4- carbonitrile::US12077506, Compound I-15

SMILES CC1(O)c2c(ccc(Oc3cc(F)cc(c3)C#N)c2C#N)C(F)(F)C1(F)F

InChI Key InChIKey=QNLOZMOQNIVKJU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694248   

TargetVascular endothelial growth factor A(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM694248(5-(3-cyano-5-fluorophenoxy)-1,1,2,2-tetrafluoro-3-...)
Affinity DataEC50:  287nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2alpha was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
US Patent