BDBM694370 US12077605, Compound PF-07321332

SMILES CC1[C@H]2CN([C@@H]([C@@H]12)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=FEECZRRIVKANPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 694370   

TargetReplicase polyprotein 1ab(2019-nCoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM694370(US12077605, Compound PF-07321332 | US20250188102, ...)
Affinity DataIC50: 18nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a [P3395H](2019-nCoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM694370(US12077605, Compound PF-07321332 | US20250188102, ...)
Affinity DataIC50: 30nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Anixa Biosciences

US Patent
LigandPNGBDBM694370(US12077605, Compound PF-07321332 | US20250188102, ...)
Affinity DataIC50: 150nMAssay Description:Representative Compounds of the Disclosure, PF-00835231, and PF-07321332 were tested for their capability to inhibit the SARS-CoV-2 main protease Mpr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab [E3429V](2019-nCoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM694370(US12077605, Compound PF-07321332 | US20250188102, ...)
Affinity DataIC50: 3.67E+4nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent