BDBM694476 US20240293412, Compound TABLE2.29

SMILES Cc1ccc(cc1)-n1cc2c(ncnc2n1)N1CCCC(C1)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=RGMDZARKXXWNDS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 694476   

TargetNicotinamide phosphoribosyltransferase(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM694476(US20240293412, Compound TABLE2.29)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of C-terminal His6-tagged wild type human NAMPT using NAM and PRPP as substrates measured for 1 hr by NMNAT1-coupled e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM694476(US20240293412, Compound TABLE2.29)
Affinity DataEC50: >2.00E+4nMAssay Description:All FP measurements were performed at room temperature in PBS buffer containing 0.01% Triton-X 100 and 1% DMSO in black 384-well plates. Measurements...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent