BDBM694611 US20240294509, Compound 21

SMILES FC(F)(F)C1CC(=NNC1=O)N1C[C@@H](C[C@H]1CCC(=O)N1CCN(CC1)c1ncc(cn1)C(F)(F)F)Oc1ccccc1

InChI Key InChIKey=LBCRVQOCKRRJPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 694611   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Euregen Biopharma Co.

US Patent
LigandPNGBDBM694611(US20240294509, Compound 21)
Affinity DataIC50: 3.40nMAssay Description:(1) Pre-coating: Add 100 μL of a PBS buffer (10 mM NaH2PO4, 10 mM Na2HPO4, 150 mM NaCl, pH 7.4) containing 20 g/mL of histone to each well of a ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Euregen Biopharma Co.

US Patent
LigandPNGBDBM694611(US20240294509, Compound 21)
Affinity DataIC50: 816nMAssay Description:(1) Pre-coating: Add 100 μL of a PBS buffer (10 mM NaH2PO4, 10 mM Na2HPO4, 150 mM NaCl, pH 7.4) containing 20 g/mL of histone to each well of a ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent