BDBM694623 US20240294509, Compound 36

SMILES CCO[C@H]1C[C@@H](CCC(=O)N2CCN(CC2)c2ncc(cn2)C(F)(F)F)N(C1)c1cc(c(=O)[nH]n1)C(F)(F)F

InChI Key InChIKey=DETVQHYFSHWWBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 694623   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Euregen Biopharma Co.

US Patent
LigandPNGBDBM694623(US20240294509, Compound 36)
Affinity DataIC50: 3.80nMAssay Description:(1) Pre-coating: Add 100 μL of a PBS buffer (10 mM NaH2PO4, 10 mM Na2HPO4, 150 mM NaCl, pH 7.4) containing 20 g/mL of histone to each well of a ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Euregen Biopharma Co.

US Patent
LigandPNGBDBM694623(US20240294509, Compound 36)
Affinity DataIC50: 14.4nMAssay Description:(1) Pre-coating: Add 100 μL of a PBS buffer (10 mM NaH2PO4, 10 mM Na2HPO4, 150 mM NaCl, pH 7.4) containing 20 g/mL of histone to each well of a ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent